Allergic Rhinitis: A Clinical and Pathophysiological Overview
Allergic rhinitis (AR) represents a global health concern where it affects approximately 400 million people worldwide. The prevalence of AR has increased over the years along with increased urbanisation and environmental pollutants thought to be some of the leading causes of the disease. Understanding the pathophysiology of AR is crucial in the development of novel therapies to treat this incurable disease that is often comorbid with other airway diseases. Hence in this mini review, we summarise the well-established yet vital aspects of AR. These include the epidemiology, clinical and laboratory diagnostic criteria, AR in paediatrics, pathophysiology of AR, Th2 responses in the disease, as well as pharmacological and immunomodulating therapies for AR patients.
Modern Medicine – Issue 4 2022