Issue 4, 2020

The latest Issue of Modern Medicine is available for you to read. We have some great articles featured in this edition; topics covered include:​

  • Ethics (CPD) – When a doctor becomes a patient
  • Pulmonology (CPD) – Asthma and COVID risk
  • CNS – Adult Bipolar Disorder
  • Woundcare – Moisture management
  • Cardiology (CPD) – Atrial Fibrillation Management
  • Gastroenterology (CPD) – Eosinophilic Oesophagitis
  • … and many more !

Also, a reminder that, not only do we have CPD questions available within the magazine itself, we also have an online CPD portal that allows you to score even more points by simply completing your test online

Modern Medicine, the journal that’s with you wherever you go.

Considerations when Prescribing Topical Corticosteroids

Considerations when Prescribing Topical Corticosteroids

Topical corticosteroids are one of the oldest and most useful treatments for dermatologic conditions. There are many topical steroids available, and they differ in potency and formulation. Successful treatment depends on an
accurate diagnosis and consideration of the steroid’s delivery vehicle, potency, frequency of application, duration of treatment, and side effects.

Modern Medicine – Issue 4 2020

Timely Diagnosis of Pancreatic Exocrine Insufficiency is Key

Timely Diagnosis of Pancreatic Exocrine Insufficiency is Key

Pancreatic exocrine insufficiency (PEI) may be caused by pancreatic disorders, including chronic pancreatitis (CP), cystic fibrosis (CF), pancreatic resection and pancreatic cancer. PEI may also result from extra-pancreatic conditions, including coeliac disease, Zollinger-Ellison syndrome and gastric surgery.

Modern Medicine – Issue 4 2020

Therapeutic Drug Monitoring Increasing IBD Treatment Efficacy

Therapeutic Drug Monitoring Increasing IBD Treatment Efficacy

Infliximab, adalimumab and other tumour necrosis factor inhibitors have revolutionised the treatment of several immune mediated inflammatory diseases. Still, many patients do not respond sufficiently to therapy or lose efficacy over time. Therapeutic drug monitoring (TDM), an individualised treatment strategy based on systematic assessments of serum drug concentrations, has been proposed as a clinical tool to optimise efficacy of
treatment.

Modern Medicine – Issue 4 2020

More Than Just Reflux: The Era of Eosinophilic Oesophagitis

More Than Just Reflux: The Era of Eosinophilic Oesophagitis

Eosinophilicoesophagit is (EoE) is a unique form of nonimmunoglobulin E (IgE) mediated food allergy. Adults with EoE typically present with food bolus impaction and/or dysphagia to solid foods. Children can have a more varied presentation, such as heartburn, failure to thrive, persistent vomiting or chronic abdominal pain. Allergy tests are not useful. First-line management options include proton pump inhibitors (PPIs), topical corticosteroids or dietary management. Response to PPIs and resolution of eosinophilia will occur in many patients with EoE.

Modern Medicine – Issue 4 2020

Fenofibrate and Cardiovascular Outcomes in Statin Users with Metabolic Syndrome

Fenofibrate and Cardiovascular Outcomes in Statin Users with Metabolic Syndrome

A propensity matched cohort study, by Kim et al. (2019), investigated fenofibrate as an add-on to statin treatment to reduce persistent cardiovascular risk in adults with metabolic syndrome in real-world settings. Results showed a significantly lower risk of major cardiovascular events compared with statin treatment alone.

Modern Medicine – Issue 4 2020

Atrial Fibrillation Management The central role of the GP

Atrial Fibrillation Management The central role of the GP

Opportunistic screening for atrial fibrillation (AF) is recommended for all patients aged over 65 years, and choosing between a rate and rhythm control strategy is important. Beta-blockers or nondihydropyridine calcium
channel antagonists are the first choice for rate control.
Flecainide is preferable for the pharmacologic rhythm control. The sexless CHA2DS2-VA assessment is recommended to assess stroke risk. Integrated care to support comprehensive treatment and address the specific needs of people with AF is required, and GPs are central to its effective delivery.

Modern Medicine – Issue 4 2020

Hypertension, Drugs and COVID-19 Risk

Hypertension, Drugs and COVID-19 Risk

Arterial hypertension is the leading cause of death in the world and is frequently accompanied by other comorbidities such as diabetes, obesity, chronic kidney disease and established cardiovascular disease of different types. Patients suffering from infection by SARS-CoV-2 frequently present with arterial hypertension and these accompanying comorbidities. Concern has been expressed that medical therapy for cardiovascular disease might specifically contribute to the severity of illness in patients with COVID-19.

Modern Medicine – Issue 4 2020

Nanocrystalline Silver Dressings Support Antimicrobial Stewardship

Nanocrystalline Silver Dressings Support Antimicrobial Stewardship

Antimicrobial resistance is an ever-increasing global concern, with the era of untreatable infection becoming a reality. Wound care is no exception, with increasing issues of antibiotic-resistant infections across different wound types and care settings. There is an urgent need for novel anti-biofilm strategies and novel antimicrobial agents and, in this scenario, silver nanotechnology has received tremendous attention in recent years in therapeutically enhanced healthcare.

Modern Medicine – Issue 4 2020