Novel Treatment for Unresectable Metastatic Melanoma – MM1502
South Africa, according to the South African Melanoma Advisory Board, has one of the highest incidences of melanoma cancers in the world. While melanoma is the most deadly form of skin cancer, a greater insight into the immune system has led to the launch of the immune checkpoint inhibitor, ipilimumab, for the treatment of advanced (unresectable or metastatic) melanoma.
Modern Medicine – February 2015
Telmisartan More Than an Antihypertensive – MM1502
Telmisartan, a well established angiotensin type 1 receptor antagonist,
is indicated for the reduction of cardiovascular morbidity in patients with manifest atherothrombotic cardiovascular disease (CVD) or type 2 diabetes mellitus with documented target organ damage, as well as for the treatment of hypertension.
Modern Medicine – February 2015
The January 2015 edition of Modern Medicine is available now.
We include a number of interesting topics for our readers, including Pain, Antibiotics and Neurology. In addition, we include our regular CPD content and an update on the upcoming conferences planned for the next two months.
Other features in this edition:
Pain | Complementary Medicine | Gastroenterology | Asthma | Psychiatry
It’s fast and intuitive and it’s only a click away.
Beyond Superbugs: Critical Lessons in Life and Medicine – MM1501
Infections and infectious diseases account for an exceedingly significant proportion of deaths that occur annually worldwide. The emergence of multi-drug resistant, extensively resistant and pan-resistant pathogens and the widespread inappropriate use of antibiotics is a global catastrophe receiving increasing attention by health care authorities.
Modern Medicine – January 2015
Cyclobenzaprine ER Single-dose for 24h Muscle Spasm Relief – MM1501
Cyclobenzaprine Hydrochloride extendedrelease capsules, marketed in South Africa as Myprocam, is indicated for the relief of muscle spasms associated with acute and painful musculoskeletal conditions. The once daily dose improves compliance with fewer peaks and troughs associated with the immediate release version.
Modern Medicine – January 2015
Human Intestinal Microbiome Changes Over Time – MM1501
Recent developments in next generation sequencing (NGS) methods have facilitated the performance of metagenomic studies to determine gut microbiome composition. These methods, together with the use of gnotobiotic animals have demonstrated the importance of the microbiota for host health, providing the basis for the use of dietary interventions aimed at counteracting microbiota aberrancies.
Modern Medicine – January 2015
Schizophrenia is at Least Partly a Inflammatory Response – MM1501
Schizophrenia (SZ) is a complex, heterogeneous disease characterised by psychosis, affecting approximately 1% of the population. Core negative symptoms of SZ include cognitive deficits, social avoidance and flat affect; positive symptoms include paranoia, hyperactivity and psychosis. Linkage analyses reflect a high impact of genetics on incidence of SZ, although environmental effects such as life events and prenatal and early development may contribute to the disease.
Modern Medicine – January 2015
Generalised Epilepsy Due to Function Abnormalities – MM1501
Primary generalised epilepsy, also called idiopathic generalised epilepsy (IGE), refers to an epilepsy syndrome of idiopathic or unknown cause, not attributed to a known underlying condition such as brain tumour, stroke or other neurological disorder. IGE is characterised by bilateral spike–wave epileptiform discharges on electroencephalography (EEG). There are a number of different IGE syndromes. Each syndrome has its own characteristic seizure type(s), typical age of onset, and specific EEG patterns.
Modern Medicine – January 2015
Omega-3 Fatty Acids for Managing Mood Disorders – MM1501
A decade ago research indicated a likely causal link between low levels of omega-3 fatty acids (FAs) and a higher prevalence of mood disorders, and also provided quite strong support for omega-3 FAs as both an antidepressant monotherapy and an augmentor of formal antidepressant drugs. Recent research is somewhat less convincing about their antidepressant efficacy but is nevertheless furthering our understanding by quantifying differential efficacy across the FAs.
Modern Medicine – January 2015
Breaking the Cycle of Acute Muscle Spasm – MM1501
A spasm is a sudden, involuntary contraction of a muscle or group of muscles, often accompanied by a sudden burst of pain which normally ceases after a few minutes. The spasm-pain-spasm of skeletal muscle spasm causes local ischemia and pain, exacerbating the spasm, which in turn exacerbates the pain. Breaking the cycle can prevent the condition from becoming chronic.
Modern Medicine – January 2015
