Unpacking the Importance of a Healthy Gut

Unpacking the Importance of a Healthy Gut – MM1706

If the latest health trends have been followed, one would know that gut health is a topical theme within the health
and wellness sphere. According to the latest research by Gut Microbiota News Watch, the status of one’s gut
microbes impact everything from inflammation and weight to one’s skin, brain health and most importantly one’s
state of mind.

Modern Medicine – June 2017

Stroke and TIA: Crucial Knowledge for a Critical Event

Stroke and TIA: Crucial Knowledge for a Critical Event – MM1706

Accurate diagnosis of stroke relies on the identification of acute onset
focal neurological syndromes. Rapid assessment, triage and
management are essential in patients with acute stroke. Patients
with a transient ischaemic attack should be rapidly assessed
and investigated, especially for symptomatic carotid stenosis
and atrial fibrillation. When an acute stroke is recognised in the
community, the patient should be transferred by ambulance
to the nearest hospital with the appropriate stroke services.
Premedication with aspirin is not appropriate as it is impossible to
confidently distinguish ischaemic stroke from intracerebral
haemorrhage without a CT scan of the brain.

Modern Medicine – June 2017

Iron Deficiency Impacts Life Quality

Iron Deficiency Impacts Life Quality – MM1706

Iron deficiency (ID) is the most common and widespread nutritional disorder in the world; 2 billion people >30% of the world’s population are anaemic, many
because of ID. ID is the only nutrient deficiency that is also prevalent in industrialised countries,1 particularly in women of childbearing age with heavy menstrual
flow and miscarriages. In clinical practice, several chronic conditions are also associated with ID.

Modern Medicine – June 2017

Ethical Considerations of Sterilisation as a Contraceptive

Ethical Considerations of Sterilisation as a Contraceptive – MM1706

Is it ethical to sterilise a young woman who has decided that she never wants children, even if there are no strong medical reasons to avoid pregnancy?
Although sterilisation is among the most straightforward surgical procedures it is enormously complex when considered from a historical, sociological,
or ethical perspective. Permanent sterilisation permits heterosexually active women to enjoy their sexual lives without fear of pregnancy. Sterilisation is
therefore a route to reproductive autonomy for many women. At the same time, it can also result in reproductive injustice.

Modern Medicine – June 2017

May 2017 Edition

We welcome you to come and read through our latest, May, edition of Modern Medicine.

This month we have a jam packed edition for you to help you cope with the freezing temperature. Our features this month include; Cardiology, Nutrition, Nephrology and many more.

We encourage all of our readers to complete the CPD questionnaire for this edition, this can be done on the answer-form included in the magazine, or on our website CPD system.

Modern Medicine, the journal that’s with you wherever you go.

Hard to Swallow? The Tale of Eosinophilic Oesophagitis

Hard to Swallow? The Tale of Eosinophilic Oesophagitis – MM1705

Eosinophilic oesophagitis (EoE) is a chronic immune- or antigen-mediated oesophageal disease. Although EoE is often similar in presentation to gastrooesophageal reflux disease (GORD), especially in young children, its symptoms do not resolve when optimally treated with antireflux medication. Symptoms of EoE are age-dependent. Adolescents and adults often present with dysphagia, odynophagia and food impaction. Corticosteroids can be extremely effective in inducing remission but discontinuation of treatment may result in relapse. Greater awareness of this disease is necessary for early diagnosis and treatment and thus prevention of sequelae such as oesophageal fibrosis and stricturing disease.

Modern Medicine – May 2017

Low Temperatures See Winter Ailments Showing Up

Low Temperatures See Winter Ailments Showing Up – MM1705

Respiratory tract infections are the most common infections worldwide, and a source of significant morbidity and a considerable economic burden to health care. Seasonal variation in the outbreaks of viral infections is a common phenomenon, with peaks often being observed during the winter months. The reasons for the higher incidence of RTIs in winter have remained controversial, and several causal factors such as changes in host physiological susceptibility, immune function, behaviour (eg, crowding) and climatic factors (temperature, relative humidity) have been suggested in this context.

Modern Medicine – May 2017

Aflibercept’s Real-world Data Shows Good Outcomes

Aflibercept’s Real-world Data Shows Good Outcomes – MM1705

Central vision loss caused by age-related macular degeneration is the leading cause of blindness among the elderly in developed countries. Clinical trial outcomes in neovascular age-related macular degeneration often have not been replicated in routine clinical practice, partly due to the difficulty for patients, carers, and health care providers following optimum treatment regimens, leading to under-treatment, and also because real-world cohorts of patients and measurement techniques are different from those in randomised controlled clinical trials.

Modern Medicine – May 2017

Understanding the Kidney – Bone Endocrine Axis

Understanding the Kidney – Bone Endocrine Axis – MM1705

Bone provides the structural framework for the human body, protecting internal organs and maintaining mineral ion balance. Bone is a target organ for several hormones such as parathyroid hormone, 1,25-dihydroxyvitamin D [1,25(OH)2D], calcitonin and sex hormones. Recent studies found important roles of bone-derived factors including osteocalcin and fibroblast growth factor 23 in systemic regulation of glucose and phosphate metabolism, respectively. Optimal phosphate balance is essential for normal skeletal growth, development and maintenance. However, maintaining optimal phosphate levels is a significant clinical challenge in various osteo-renal diseases because phosphate toxicity has a wide range of harmful effects and because its therapeutic control is difficult, particularly in patients with chronic kidney disease.

Modern Medicine – May 2017