Systemic sclerosis (SSc), or scleroderma, is a multisystem autoimmune disease characterised by vasculopathy and fibrosis. Adultonset Raynaud’s phenomenon or Raynaud’s phenomenon complicated by digital ulceration or infarction should prompt consideration of connective tissue disorders including SSc. Early identification of severe, lifethreatening organ manifestations can result in improved quality of life and survival. Management of patients with SSc is multifaceted and dependent on individual disease manifestations.
Modern Medicine – May/June 2018