A Clinical Approach to Managing Obesity in Adults

A Clinical Approach to Managing Obesity in Adults

Obesity is a complex chronic disease that is strongly associated with an increased risk of all-cause mortality. Routine screening is required to assess the complications of obesity. Therapies for managing obesity should be guided by an individual’s body mass index, comorbidities and the presence and severity of obesity-related complications.

Modern Medicine – Issue 4 2023

Early Intervention Alters the Prediabetes Trajectory

Early Intervention Alters the Prediabetes Trajectory

Prediabetes is a high-risk state for progression to diabetes with an annualised conversion rate of 5–10%, with a similar proportion converting back to normoglycaemia. Proactive screening and a prompt lifestyle intervention in those with incident prediabetes is effective in preventing the progression to type 2 diabetes in many patients. The addition of metformin has a selectively greater impact in certain categories of patients.

Modern Medicine – Issue 4 2023

An Update on Clinical Prospectsand Management of Osteoarthritis

An Update on Clinical Prospects and Management of Osteoarthritis

The rising prevalence of osteoarthritis (OA) in the general population has necessitated the development of novel treatment options. Over the next few years, several prospective therapies focusing on inflammation, cartilage metabolism, subchondral bone remodelling, cellular senescence and the peripheral nociceptive pathway are predicted to transform the OA therapy landscape. This is a shortened version of the original open access articles.

Modern Medicine – Issue 4 2023

Fluid Regulation is Vital inHypertension Management

Fluid Regulation is Vital in Hypertension Management

Fluid balance is inextricably linked with electrolyte balance, both in the intracellular (rich in K+ ions) and extracellular (rich in Na+ & Cl- ions) compartments, where trading of electrolytes is the core strategy of renal fluid regulation. Medicinal products that affect renal regulation of electrolyte excretion have a significant effect in terms of the quantity of fluid control and thus water homeostasis.

Modern Medicine – Issue 4 2023

Lipid Levels – Important Clues for Cardio and Pancreas Health

Lipid Levels – Important Clues for Cardio and Pancreas Health

Hypertriglyceridemia (HTG), as an important component of atherogenic dyslipidaemia and a cardiovascular disease risk factor, should be carefully evaluated and managed via lifestyle modification and pharmacotherapy. Although statins form a basis of the contemporary lipid-modifying treatment, major trials support the findings that therapy with fibrates is most beneficial in patients with triglyceride levels above 204mg/dL and high-density lipoprotein cholesterol (HDL-C) below 34mg/dL.

Modern Medicine – Issue 4 2023

Iron Micro Particles Improve Digestibility

Iron Micro Particles Improve Digestibility

Iron deficiency is one of the most important nutritional disorders, and can cause health problems. Food fortification with minerals often induces unacceptable organoleptic changes during the preparation process and storage, has low bioavailability and solubility, and is expensive. Micro particle surface modification to obtain novel characteristics can be a useful tool to overcome these problems.

Modern Medicine – Issue 4 2023

Expedite Labour with a VacuumAssisted Delivery

Expedite Labour with a Vacuum Assisted Delivery

Complications during childbirth result in the need for clinicians to use ‘assisted delivery’ in over 12% of cases (UK statistics). After more than 50 years in clinical practice, vacuum assisted delivery (VAD) devices remain a mainstay in physically assisting child delivery; sometimes preferred over forceps due to their ease of use and reduced maternal morbidity.

Modern Medicine – Issue 4 2023

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