Atopic dermatitis (AD) is a common eczematous skin disorder affecting 2-20% of the general population. AD is characterised by chronic cutaneous inflammation and dry skin with epidermal barrier dysfunction. Intense pruritus is the major and burdensome symptom of AD. Itch induced scratching appears to exacerbate skin inflammation by accelerating cellular damage in the lesional skin. Approximately 80% of AD patients exhibit elevated levels of serum IgE.
Modern Medicine – Dec/Jan 2019