Endocrinology

Navigating the New Diabetes Drugs Cardiovascular benefits and when to use

Navigating the New Diabetes Drugs Cardiovascular benefits and when to use

The recent introduction of antihyperglycaemic medications that not only improve glycated haemoglobin (HbA1c) levels but also provide cardiovascular, renal and overall mortality benefit renews hope for better management of diabetes. The new sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists are potential game changers for people with T2D. Evidence shows that besides improving glyacaemic control, these drugs have renal, cardiovascular and all-cause mortality benefits.

Modern Medicine – Issue 5 2020

Timely Diagnosis of Pancreatic Exocrine Insufficiency is Key

Timely Diagnosis of Pancreatic Exocrine Insufficiency is Key

Pancreatic exocrine insufficiency (PEI) may be caused by pancreatic disorders, including chronic pancreatitis (CP), cystic fibrosis (CF), pancreatic resection and pancreatic cancer. PEI may also result from extra-pancreatic conditions, including coeliac disease, Zollinger-Ellison syndrome and gastric surgery.

Modern Medicine – Issue 4 2020

Addison’s Disease Managing ‘Sick Days’ to Avoid Crises

Addison’s Disease Managing ‘Sick Days’ to Avoid Crises – MM1601

Integral to the body’s stress system, an increase in cortisol levels is critical to surviving illness. Timely administration of exogenous glucocorticoids in doses designed to mimic this response is essential in preventing an episode of adrenal insufficiency or crisis in patients who lack their own cortisol, such as in those with Addison’s disease.

Modern Medicine – January 2016

Hypothyroidism: A Definitive Diagnosis Guides Treatment

Hypothyroidism: A Definitive Diagnosis Guides Treatment – MM1508

Hypothyroidism may be obvious clinically but it has a wide spectrum of severity and can be very subtle. Many people with a normal thyroid function may present to GPs with complaints of mild symptoms suggestive of hypothyroidism. Therefore, biochemical confirmation of true hypothyroidism is mandatory. There is no evidence that thyroxine treatment of suggestive symptoms is beneficial when tests are normal.

Modern Medicine – August 2015

Diabetes as the Years Progress: How Does Management Differ?

Diabetes as the Years Progress: How Does Management Differ? – MM1502

It is important to recognise the various functional, medical and social issues that the elderly population with diabetes face and to use the expertise of multiple disciplines to deliver a safe and effective management plan, which needs to be as simple to follow as possible.

Modern Medicine – February 2015

Game Changers in Type 2 Diabetes: Adding Insulin to Hypoglycaemics

Game Changers in Type 2 Diabetes: Adding Insulin to Hypoglycaemics – MM1408

The first three medication steps in long-term glycaemic control for people with type 2 diabetes are relatively easy – the use of one, then two and then three hypoglycaemic agents – but doctors and patients are often reluctant to take the next step and may unnecessarily delay starting insulin therapy.

Modern Medicine – August 2014

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