Deconditioning describes functional decline, progressive weakness and physiological changes that result from prolonged bed rest and inactivity. Frailty is a syndrome in which age-related physiological changes
are accelerated or exacerbated in multiple systems. Multisystem changes can occur within 24 hours of bed rest; these changes worsen with prolonged inactivity, potentially requiring more time to reverse (where possible). Deconditioning is more likely in patients who experience frailty. Due to the complexities
of these conditions, optimal management involves a multidisciplinary team comprised of GPs, specialists and allied health professionals.
