Neuroendocrine neoplasms (NEN s) arise from the diffuse neuroendocrine cell system and may occur at many different disease sites. Most frequently, these neoplasms occur in the digestive system, followed by the lung. The term NEN encompasses well-differentiated neuroendocrine tumours (NE Ts) and poorly differentiated neuroendocrine carcinomas (NECs). NECs represent only 10%–20% of all NEN s. The main focus of these guidelines is on sporadic small intestinal (SI)- NENs and pancreatic NENs (Pan-NENs) since these are the most prevalent NEN s at advanced disease stages. This is a shortened version of the original article.
Modern Medicine – Issue 5 2021