Eosinophilicoesophagit is (EoE) is a unique form of nonimmunoglobulin E (IgE) mediated food allergy. Adults with EoE typically present with food bolus impaction and/or dysphagia to solid foods. Children can have a more varied presentation, such as heartburn, failure to thrive, persistent vomiting or chronic abdominal pain. Allergy tests are not useful. First-line management options include proton pump inhibitors (PPIs), topical corticosteroids or dietary management. Response to PPIs and resolution of eosinophilia will occur in many patients with EoE.
Modern Medicine – Issue 4 2020