Musculoskeletal pain is common and has significant consequences for affected patients and society as a whole. Musculoskeletal pain is not purely nociceptive; peripheral inflammation and central sensitisation processes, as well as neuropathic components, contribute. Management of patients with these conditions should be multimodal and multidisciplinary and follow principles of chronic disease management aiming for improved function. Nonopioid analgesics play an important role in the pharmacological management of patients. Opioids should be used with caution and only after careful consideration in patients with musculoskeletal pain. Adjuvants such as anticonvulsants and antidepressants may play a previously underestimated role in the management of patients with musculoskeletal pain.
Modern Medicine – Oct/Nov 2018