Gastroenterology

Pantoprazole Reduces GI Damage in Critical Patients

Pantoprazole Reduces GI Damage in Critical Patients – MM1507

Pantoprazole is an irreversible proton pump inhibitor (PPI) that reduces gastric acid secretion. PPIs achieve a greater degree and longer duration of gastric acid suppression and better healing rates in various gastric acid-related disorders than histamine H2 receptor antagonists, making them essential in the management of gastrooesophageal reflux disease, peptic ulcer disease and Zollinger–Ellison syndrome.

Modern Medicine – July 2015

Effective Bowel Cleansing Improves Examination Results

Effective Bowel Cleansing Improves Examination Results – MM1504

Colonoscopy constitutes the principal investigation for colorectal neoplasms due to its ability to detect and remove most of precancerous lesions. Diagnostic accuracy and therapeutic safety of colonoscopy strictly depends upon the quality of bowel cleansing. The ideal preparation for colonoscopy should reliably empty the colon from all faecal material allowing the optimal visualisation of the entire colonic mucosa without causing great patient discomfort or significant shifts in fluids and electrolytes.

Modern Medicine – April 2015

Pointers for Increasing Colonoscopy Efficacy

Pointers for Increasing Colonoscopy Efficacy – MM1504

In the past decade, the colonoscopy procedure has been largely studied to improve colorectal lesions detection resulting in the identification of quality indicators for colonoscopy procedure. Successful colonoscopy depends upon a number of factors including correct cecum intubation, cleaning of the colon, careful mucosal inspection and operator experience. With the rapidly rising costs of healthcare and the need to rationalise spending, it is important to spare costly repeat procedures, as in the cases of incomplete colonoscopy. Bowel preparation is essential for both the quality of the colonoscopy and the adenoma or adenocarcinoma detection rate.)

Modern Medicine – April 2015

Novel Treatment for Ulcerative Colitis Improves Compliance

Novel Treatment for Ulcerative Colitis Improves Compliance – MM1503

Ulcerative Colitis is a form of inflammatory bowel disease producing inflammation and ulcers along the inside of the colon, which can interfere with the normal function of the colon, often causing cramping, bloating, diarrhoea, bleeding, fatigue, weight loss and frequent bowel movements, which may also strongly affect quality of life. The 2011 reported incidence of ulcerative colitis was 1.2 to 20.3 cases per 100 000 persons per year with a prevalence of 7.6 to 246 cases per 100 000 per year.

Modern Medicine – March 2015

Human Intestinal Microbiome Changes Over Time

Human Intestinal Microbiome Changes Over Time – MM1501

Recent developments in next generation sequencing (NGS) methods have facilitated the performance of metagenomic studies to determine gut microbiome composition. These methods, together with the use of gnotobiotic animals have demonstrated the importance of the microbiota for host health, providing the basis for the use of dietary interventions aimed at counteracting microbiota aberrancies.

Modern Medicine – January 2015

Small Bowel Video Capsule Endoscopy

Small Bowel Video Capsule Endoscopy – MM1410

Video capsule endoscopy (VCE) is an important and useful tool in assessing the small intestine. Its main indication is in patients with recurrent and/or persistent bleeding in the small bowel for which no source has been found on gastroscopy and colonoscopy. VCE is the most sensitive and specific non-invasive test available for detecting mucosal changes in the small bowel.

Modern Medicine – October 2014

Herbal Drug Rivals PPIs in Breakthrough Clinical Trial

Herbal Drug Rivals PPIs in Breakthrough Clinical Trial – MM1307

Results from a breakthrough clinical trial investigating the efficacy and tolerability of treatments for functional dyspepsia (FD) have revealed that the natural medicine Iberogast worked as well as a proton pump inhibitor (esomeprazole), with less chance of symptoms recurring after stopping treatment.

Modern Medicine – July 2013

Verified by ExactMetrics