{"id":1760,"date":"2018-01-31T13:44:37","date_gmt":"2018-01-31T11:44:37","guid":{"rendered":"http:\/\/www.modernmedia.co.za\/modernmedicine\/?p=1760"},"modified":"2018-01-31T13:44:37","modified_gmt":"2018-01-31T11:44:37","slug":"elevated-serum-ferritin-identifying-iron-overload","status":"publish","type":"post","link":"http:\/\/www.modernmedia.co.za\/modernmedicine\/?p=1760","title":{"rendered":"Elevated Serum Ferritin Identifying Iron Overload"},"content":{"rendered":"<p><a href=\"http:\/\/www.modernmedia.co.za\/modernmedicine\/DigitalEditions\/mm1801-january-2018\/html5\/index.html\">Elevated Serum Ferritin Identifying Iron Overload<\/a><\/p>\n<p>Ferritin, an iron storage protein, is critical to iron haemostasis. Alterations in ferritin level are seen commonly<br \/>\nin clinical practice, often reflecting perturbations in iron homeostasis or metabolism. Ferritin is an acute-phase<br \/>\nreactant that can become elevated in several conditions related to inflammation or infections. Hyperferritinaemia<br \/>\nis seen in patients who misuse alcohol and patients with fatty liver disease. Raised ferritin levels are also caused<br \/>\nby overexpression of tissue ferritin in a number of cancers. The most common iron overload condition is hereditary<br \/>\nhaemochromatosis. Haemophagocytic syndrome is a heterogeneous group of disorders with a final common<br \/>\npathway consisting of hyperferritinaemia, pancytopenia, splenomegaly and multiple organ failure.<\/p>\n<p><em>Modern Medicine \u2013\u00a0January 2018<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Elevated Serum Ferritin Identifying Iron Overload Ferritin, an iron storage protein, is critical to iron haemostasis. Alterations in ferritin level are seen commonly in clinical practice,&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2},"beyondwords_generate_audio":"","beyondwords_project_id":"","beyondwords_content_id":"","beyondwords_preview_token":"","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"categories":[1],"tags":[],"class_list":["post-1760","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5REYo-so","_links":{"self":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1760"}],"version-history":[{"count":1,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1760\/revisions"}],"predecessor-version":[{"id":1761,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1760\/revisions\/1761"}],"wp:attachment":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1760"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1760"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}