{"id":1323,"date":"2016-08-29T09:19:19","date_gmt":"2016-08-29T07:19:19","guid":{"rendered":"http:\/\/www.modernmedia.co.za\/modernmedicine\/?p=1323"},"modified":"2016-08-29T09:19:19","modified_gmt":"2016-08-29T07:19:19","slug":"osteoarthritis-factors-associated-with-pain-and-implications-for-therapy","status":"publish","type":"post","link":"http:\/\/www.modernmedia.co.za\/modernmedicine\/?p=1323","title":{"rendered":"Osteoarthritis Factors Associated with Pain and Implications for Therapy"},"content":{"rendered":"<p><a href=\"http:\/\/www.modernmedia.co.za\/modernmedicine\/DigitalEditions\/mm1608-august-2016\/index.html\" target=\"_blank\">Osteoarthritis Factors Associated with Pain and Implications for Therapy \u2013 MM1608<\/a><\/p>\n<p>Osteoarthritis is an umbrella term for several processes that\u00a0lead to pain and cartilage loss. X-rays give limited information\u00a0and only provide marginal assistance at tailoring therapy\u00a0for the individual. MRI has great potential in this regard but\u00a0targeted trials have been few to date. Bone marrow lesions and\u00a0cartilage defects have independent associations with pain in\u00a0people with osteoarthritis. Obesity and weak muscles are also\u00a0independently associated with pain in osteoarthritis; therefore,\u00a0weight loss, strengthening and aerobic exercises help improve\u00a0symptoms. Pain in osteoarthritis is modified by central factors\u00a0such as depression, catastrophisation, self-efficacy and a\u00a0positive attitude. Targeting subchondral bone has the most\u00a0potential to modify osteoarthritis given the failure of most\u00a0therapies aimed at cartilage.<\/p>\n<p><em>Modern Medicine \u2013 August\u00a02016<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Osteoarthritis Factors Associated with Pain and Implications for Therapy \u2013 MM1608 Osteoarthritis is an umbrella term for several processes that\u00a0lead to pain and cartilage loss. X-rays&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2},"beyondwords_generate_audio":"","beyondwords_project_id":"","beyondwords_content_id":"","beyondwords_preview_token":"","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"categories":[57,183,11,59],"tags":[],"class_list":["post-1323","post","type-post","status-publish","format-standard","hentry","category-arthritis","category-osteoarthritis","category-pain","category-rheumatology"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5REYo-ll","_links":{"self":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1323","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1323"}],"version-history":[{"count":1,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1323\/revisions"}],"predecessor-version":[{"id":1324,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1323\/revisions\/1324"}],"wp:attachment":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1323"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1323"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1323"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}