{"id":1231,"date":"2016-04-21T15:05:25","date_gmt":"2016-04-21T13:05:25","guid":{"rendered":"http:\/\/www.modernmedia.co.za\/modernmedicine\/?p=1231"},"modified":"2016-04-21T15:05:25","modified_gmt":"2016-04-21T13:05:25","slug":"vortioxetine-a-new-option-for-depression","status":"publish","type":"post","link":"http:\/\/www.modernmedia.co.za\/modernmedicine\/?p=1231","title":{"rendered":"Vortioxetine A new option for depression"},"content":{"rendered":"<p><a href=\"http:\/\/www.modernmedia.co.za\/modernmedicine\/DigitalEditions\/mm1604-april-2016\/index.html\" target=\"_blank\">Vortioxetine A new option for depression \u2013 MM1604<\/a><\/p>\n<p>Vortioxetine has been approved for treatment of adults with major depressive\u00a0disorder. It adds to the repertoire of antidepressants available for individualising\u00a0treatment and may have particular benefits for patients with cognitive\u00a0impairment associated with depression.<\/p>\n<p>In vitro studies indicate that it is an inhibitor of serotonin reuptake and acts\u00a0as an agonist at the serotonin 5-HT1A receptor, partial agonist at the 5-HT1B\u00a0receptor and antagonist at the 5-HT1D, 5-HT3 and 5-HT7 receptors.<\/p>\n<p>In adults, the usual starting dose of vortioxetine is 10mg once daily, taken with\u00a0or without food at any time of day.<\/p>\n<p><em>Modern Medicine \u2013 April\u00a02016<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vortioxetine A new option for depression \u2013 MM1604 Vortioxetine has been approved for treatment of adults with major depressive\u00a0disorder. It adds to the repertoire of antidepressants&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2},"beyondwords_generate_audio":"","beyondwords_project_id":"","beyondwords_content_id":"","beyondwords_preview_token":"","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"categories":[15],"tags":[],"class_list":["post-1231","post","type-post","status-publish","format-standard","hentry","category-depression"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5REYo-jR","_links":{"self":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1231","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1231"}],"version-history":[{"count":1,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1231\/revisions"}],"predecessor-version":[{"id":1232,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=\/wp\/v2\/posts\/1231\/revisions\/1232"}],"wp:attachment":[{"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1231"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1231"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.modernmedia.co.za\/modernmedicine\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1231"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}